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武汉费斯德生物科技有限公司
主营：G蛋白活性抗体及试剂盒,非乙酰化CAMP和CGMP试剂,点突变抗体 - 18162422833
武汉费斯德生物科技有限公司
主营：G蛋白活性抗体及试剂盒,非乙酰化CAMP和CGMP试剂,点突变抗体
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| 货号: 26330 |
| 基因符号: GNAQ, CMC1, G-ALPHA-q, GAQ, SWS |
| 描述: Anti-GNAQ(Q209R) Mouse Monoclonal Antibody |
| 背景介绍: GNAQ is a protein that in humans encoded by the GNAQ gene. The GNAQ protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospholipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. |
| *原: A synthetic peptide from the internal region of GNAQ, which includes the mutation of Q209R, human origin |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: ELISA: 1: 1000-1: 2000 WB: 1: 500-1: 1000 IHC: 1: 50-1: 100 |
| 浓度: 1 mg/ml |
| 宿主: Mouse |
| 形式: Liquid |
| 克隆性: Monoclonal |
| 亚型: IgG |
| 纯度: Purified from ascites |
| 防腐剂: No |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| 种属反应性: Recognizes Q209R mutant, but not wild-type GNAQ of vertebrates |
| 储存条件: Store at -20°C. Avoid repeated freezing and thawing |
蛋白质印迹: Western blot analysis of recombinant GNAQ(Q209R) and wildtype proteins. Purified His-tagged GNAQ(Q209R) protein (lane2) and corresponding wild-type protein (lane1) were blotted with Anti-GNAQ(Q209R) monoclonal antibody (Cat. #26330). *荧光: Immunofluorescence of cells expressing GNAQ proteins with Anti-GNAQ(Q209R) antibody. HEK293T cells were transfected with p3-GFP-GNAQ(Q209R) plasmid, p3-GFP-GNAQ (WT) plasmid, p3-GFP-GNAQ (Q209L) plasmid or p3-GFP-GNAQ (Q209P) plasmid, then fixed and stained with Anti-GNAQ(Q209R) monoclonal antibody (Cat. #26330). |