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武汉费斯德生物科技有限公司
主营：G蛋白活性抗体及试剂盒,非乙酰化CAMP和CGMP试剂,点突变抗体 - 18162422833
武汉费斯德生物科技有限公司
主营：G蛋白活性抗体及试剂盒,非乙酰化CAMP和CGMP试剂,点突变抗体
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| 货号: 26249 |
| 基因符号: FGFR1, BFGFR, CD331, CEK, FGFBR, FLG |
| 描述: Anti-FGFR1(P252R) Mouse Monoclonal Antibody |
| 背景介绍: The protein FGFR1 is highly conserved between members and throughout evolution. This particular family member of FGFR1 binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations of FGFR1 protein have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer and autosomal dominant Kallmann syndrome. |
| *原: A synthetic peptide from the internal region of FGFR1, which includes the mutation of P252R, human origin |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: ELISA: 1: 1000-1: 2000 WB: 1: 500-1: 1000 IHC: 1: 50-1: 100 |
| 浓度: 1 mg/ml |
| 宿主: Mouse |
| 形式: Liquid |
| 克隆性: Monoclonal |
| 亚型: IgG |
| 纯度: Purified from ascites |
| 防腐剂: No |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| 种属反应性: Recognizes P252R mutant, but not wild-type FGFR1 of vertebrates |
| 储存条件: Store at -20°C. Avoid repeated freezing and thawing |
蛋白质印迹: Western blot analysis of recombinant FGFR1(P252R) and wildtype proteins. Purified His-tagged FGFR1(P252R) protein (22-376aa, 45KD, lane 2) and corresponding wildtype protein (lane 1) were blotted with Anti-FGFR1(P252R) monoclonal antibody (Cat. #26249). *荧光: Immunofluorescence of cells expressing FGFR1 proteins with Anti-FGFR1(P252R) antibody. HEK293T cells were transfected with p3-GFP-FGFR1 (WT) plasmid (left column) or p3-GFP-FGFR1(P252R) plasmid (right column), then fixed and stained with Anti-FGFR1(P252R) monoclonal antibody (Cat. #26249). |